Scientists from Yale University have identified new biomarkers that will help develop more effective treatment strategies to fight melanoma, the most serious form of skin cancer. The research team has mapped chemical modifications of DNA in the melanoma genome hat will open new avenues for developing improved therapies. In addition to mutations to the DNA code that can cause malignancies, epigenetic changes alterations to the chemical modifications of DNA that regulate genes are frequent in a number of diseases, including cancer. If the normal epigenetic patterns that regulate gene expression are disrupted, cellular functions can go awry and lead to disease. The team then focused on five genes in particular, three of which had not been implicated in melanoma until now.
Subscribe to:
Post Comments (Atom)
No comments:
Post a Comment